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Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis
The potent antimalarial drug pyronaridine (PND) was tested for its potential as an anticancer drug. After exposing cancerous (17) and non-cancerous (2) cells to PND for 72 hr, PND was found to exhibit consistent and potent cytotoxic activity at low micromolar (μM) concentrations that ranged from 1.6...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6218039/ https://ncbi.nlm.nih.gov/pubmed/30395606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206467 |
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