CD33/CD3-bispecific T-cell engaging (BiTE®) antibody construct targets monocytic AML myeloid-derived suppressor cells

Acute myeloid leukemia (AML) is the most common acute leukemia amongst adults with a 5-year overall survival lower than 30%. Emerging evidence suggest that immune alterations favor leukemogenesis and/or AML relapse thereby negatively impacting disease outcome. Over the last years myeloid derived sup...

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Библиографические подробности
Опубликовано в: :J Immunother Cancer
Главные авторы: Jitschin, Regina, Saul, Domenica, Braun, Martina, Tohumeken, Sehmus, Völkl, Simon, Kischel, Roman, Lutteropp, Michael, Dos Santos, Cedric, Mackensen, Andreas, Mougiakakos, Dimitrios
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Short Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217777/
https://ncbi.nlm.nih.gov/pubmed/30396365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0432-9
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