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BiTE-ing into prostate cancer with bispecific T cell engagers

Targeting prostate-specific membrane antigen (PSMA) has important therapeutic ramifications, more recently including immune oncology. Data were recently presented on the preclinical efficacy of a half-life extended bispecific T cell engager, AMG 160, which binds PSMA and CD3 to induce T cell-driven...

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Foilsithe in:Clin Cancer Res
Main Authors: Kamat, Nikhil V., Yu, Evan Y., Lee, John K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127346/
https://ncbi.nlm.nih.gov/pubmed/33707179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-21-0355
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