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Tuning the Balance between Fibrillation and Oligomerization of α-Synuclein in the Presence of Dopamine

[Image: see text] The aggregates of α-synuclein bear a close connection with Parkinson’s disease, which is largely characterized by the loss of the dopaminergic neurons. Dopamine promotes the formation of undesirable sodium dodecyl sulfate (SDS)-resistant oligomers of α-synuclein. In this study, we...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Saha, Shivnetra, Khan, Mohammad Ashhar Iqbal, Mudhara, Deepak, Deep, Shashank
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217689/
https://ncbi.nlm.nih.gov/pubmed/30411062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00993
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