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PDTM-17. DUAL TARGETING OF SHH SIGNALING AND BCL-xL FUNCTION AS A NOVEL TREATMENT FOR MEDULLOBLASTOMA

Medulloblastoma is markedly more sensitive to radiation and chemotherapy than other malignant brain tumors. We have previously shown that medulloblastomas radiation sensitivity of depends on the function of the internal apoptosis pathway. We tested whether this pathway could be directly activated, w...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Veleta, Katherine, Gershon, Timothy
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217661/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.859
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