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RDNA-06. A NOVEL ROLE OF SGEF IN MEDIATING GBM CELL SURVIVAL BY MODULATING THE DNA DAMAGE REPAIR MECHANISM

Glioblastoma (GBM) is among the most genetically heterogeneous, treatment resistant, and lethal of all human cancers. A significant hurdle to effective treatment of GBM is the aggressive invasion of tumor cells into surrounding healthy brain tissue that invariably leads to tumor recurrence, brain in...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Tuncali, Serdar, Sereduk, Christopher, Fortin Ensign, Shannon, Kloss, Jean, Sarkaria, Jann, Loftus, Joseph, Tran, Nhan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217526/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.922
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