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RDNA-06. A NOVEL ROLE OF SGEF IN MEDIATING GBM CELL SURVIVAL BY MODULATING THE DNA DAMAGE REPAIR MECHANISM

Glioblastoma (GBM) is among the most genetically heterogeneous, treatment resistant, and lethal of all human cancers. A significant hurdle to effective treatment of GBM is the aggressive invasion of tumor cells into surrounding healthy brain tissue that invariably leads to tumor recurrence, brain in...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Tuncali, Serdar, Sereduk, Christopher, Fortin Ensign, Shannon, Kloss, Jean, Sarkaria, Jann, Loftus, Joseph, Tran, Nhan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217526/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.922
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