mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level

Wnt/β-catenin signaling plays pivotal roles in cell proliferation and tissue homeostasis by maintaining somatic stem cell functions. The mammalian target of rapamycin (mTOR) signaling functions as an integrative rheostat that orchestrates various cellular and metabolic activities that shape tissue h...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Zeng, Hao, Lu, Bo, Zamponi, Raffaella, Yang, Zinger, Wetzel, Kristie, Loureiro, Joseph, Mohammadi, Sina, Beibel, Martin, Bergling, Sebastian, Reece-Hoyes, John, Russ, Carsten, Roma, Guglielmo, Tchorz, Jan S., Capodieci, Paola, Cong, Feng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217415/
https://ncbi.nlm.nih.gov/pubmed/30297426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808575115
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