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Thermodynamic favorability and pathway yield as evolutionary tradeoffs in biosynthetic pathway choice
The structure of the metabolic network contains myriad organism-specific variations across the tree of life, but the selection basis for pathway choices in different organisms is not well understood. Here, we examined the metabolic capabilities with respect to cofactor use and pathway thermodynamics...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217407/ https://ncbi.nlm.nih.gov/pubmed/30309961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805367115 |
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