Ribonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice

Producing normal eggs for fertilization and species propagation requires completion of meiosis and protection of the genome from the ravages of retrotransposons. Mutation of Marf1 (meiosis regulator and mRNA stability factor 1) results in defects in both these key processes in mouse oocytes and thus...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yao, Qingqing, Cao, Guangyi, Li, Mingzhe, Wu, Baixing, Zhang, Xiaoyun, Zhang, Teng, Guo, Jing, Yin, Hong, Shi, Lanying, Chen, Jiayi, Yu, Xiang, Zheng, Lina, Ma, Jinbiao, Su, You-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217404/
https://ncbi.nlm.nih.gov/pubmed/30333187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809744115
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