Ribonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice

Producing normal eggs for fertilization and species propagation requires completion of meiosis and protection of the genome from the ravages of retrotransposons. Mutation of Marf1 (meiosis regulator and mRNA stability factor 1) results in defects in both these key processes in mouse oocytes and thus...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Yao, Qingqing, Cao, Guangyi, Li, Mingzhe, Wu, Baixing, Zhang, Xiaoyun, Zhang, Teng, Guo, Jing, Yin, Hong, Shi, Lanying, Chen, Jiayi, Yu, Xiang, Zheng, Lina, Ma, Jinbiao, Su, You-Qiang
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217404/
https://ncbi.nlm.nih.gov/pubmed/30333187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809744115
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