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EXTH-51. C18-CERAMIDE ANALOGUE DRUG OVERCOMES RESISTANCE TO TEMOZOLOMIDE IN GLIOBLASTOMA
Glioblastoma (GB) is a WHO Grade IV brain tumor with very limited therapeutic option currently available. The DNA-alkylating agent temozolomide (TMZ) is currently the most effective chemotoxic drug for GB therapy but efficacy tends to be short-lasting with tumors eventually becoming resistant to tre...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217372/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.399 |
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