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TMIC-49. ACTIVATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY IN GLIOMA STEM CELLS IMPACTS ENDOTHELIAL CELL-CELL INTERACTION
BACKGROUND: The presence of invasive glioma stem cells (GSC) in glioblastoma (GBM) enhances therapy resistance and disease recurrence. Low permeability and high selectivity of the blood-brain barrier (BBB) limits CNS drug delivery of effective treatment against GSC growth. Moreover, increased Wnt/β-...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217120/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1108 |
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