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SCIDOT-21. IMPROVING DRUG DELIVERY TO GLIOBLASTOMA BY TARGETING CANONICAL WNT/β-CATENIN SIGNALING IN THE BLOOD-BRAIN BARRIER

BACKGROUND: Glioblastoma (GBM) patient survival and therapy response is greatly hindered by the presence of invasive glioma stem cells (GSC) and the blood-brain barrier (BBB) which limits effective drug delivery. WNT/beta-catenin signaling is important in the development and maintenance of the BBB b...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Vezina, Amelie, Jackson, Sadhana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846476/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1157
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