TMIC-49. ACTIVATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY IN GLIOMA STEM CELLS IMPACTS ENDOTHELIAL CELL-CELL INTERACTION

BACKGROUND: The presence of invasive glioma stem cells (GSC) in glioblastoma (GBM) enhances therapy resistance and disease recurrence. Low permeability and high selectivity of the blood-brain barrier (BBB) limits CNS drug delivery of effective treatment against GSC growth. Moreover, increased Wnt/β-...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Vézina, Amélie, Gilbert, Mark, Jackson, Sadhana
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217120/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1108
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