NCOG-01. PRESERVATION OF NEUROCOGNITIVE FUNCTION (NCF) WITH HIPPOCAMPAL AVOIDANCE DURING WHOLE-BRAIN RADIOTHERAPY (WBRT) FOR BRAIN METASTASES: PRELIMINARY RESULTS OF PHASE III TRIAL NRG ONCOLOGY CC001

PURPOSE: NRG CC001, a phase III trial of WBRT plus memantine with or without hippocampal avoidance, sought to evaluate the neuro-protective effects of avoiding the hippocampus using intensity-modulated radiotherapy. METHODS: Adult patients with brain metastases were stratified by RPA class and recei...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Gondi, Vinai, Pugh, Stephanie, D Brown, Paul, Wefel, Jeffrey, Gilbert, Mark, Bovi, Joseph, Robinson, Cliff, Tammie, Benzinger, Tome, Wolfgang, Armstrong, Terri, Bruner, Deborah, Khuntia, Deepak, Grosshans, David, Konski, Andre, Robidoux, Andre, Kundapur, Vijayananda, Devisetty, Kiran, Shah, Sunjay, Usuki, Kenneth, Anderson, Bethany, Stea, Baldassarre, Yoon, Harold, Li, Jing, Laack, Nadia, Kruser, Tim, Chmura, Steven, Shi, Wenyin, P Mehta, Minesh, Kachnic, Lisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217077/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.716
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