Blood exosomes regulate the tissue distribution of grapefruit-derived nanovector via CD36 and IGFR1 pathways

Tumor-specific delivery of therapeutics is challenging. One of the major hurdles for successfully delivering targeted agents by nanovectors is the filtering role of the liver in rapidly sequestering nanovectors from the circulation. Exosomes, a type of endogenous nanoparticle, circulate continuously...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Wang, Qi-long, Zhuang, XiaoYing, Sriwastva, Mukesh K., Mu, Jingyao, Teng, Yun, Deng, Zhongbin, Zhang, Lifeng, Sundaram, Kumaran, Kumar, Anil, Miller, Donald, Yan, Jun, Zhang, Huang-Ge
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217058/
https://ncbi.nlm.nih.gov/pubmed/30429877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.27608
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