Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages

Liver metastasis accounts for many of the cancer deaths in patients. Effective treatment for metastatic liver tumors is not available. Here, we provide evidence for the role of miR-18a in the induction of liver M1 (F4/80(+)interferon gamma (IFNγ)(+)IL-12(+)) macrophages. We found that miR-18a encaps...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Teng, Yun, Mu, Jingyao, Hu, Xin, Samykutty, Abhilash, Zhuang, Xiaoying, Deng, Zhongbin, Zhang, Lifeng, Cao, Pengxiao, Yan, Jun, Miller, Donald, Zhang, Huang-Ge
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041936/
https://ncbi.nlm.nih.gov/pubmed/27028860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8361
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