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Grapefruit-derived nanovectors use an activated leukocyte trafficking pathway to deliver therapeutic agents to inflammatory tumor sites

Inflammation is a hallmark of cancer. Activated immune cells are intrinsically capable of homing to inflammatory sites. Using three inflammatory driven disease mouse models, we show that grapefruit-derived nanovectors (GNVs) coated with inflammatory related receptor enriched membranes of activated l...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Wang, Qilong, Ren, Yi, Mu, Jingyao, Egilmez, Nejat, Zhuang, Xiaoyin, Deng, Zhongbin, Zhang, Lifeng, Yan, Jun, Miller, Donald, Zhang, Huang-Ge
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470740/
https://ncbi.nlm.nih.gov/pubmed/25883092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3095
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