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CSIG-29. THE DUAL PI3K/mTOR-PATHWAY INHIBITOR GDC-0084 ACHIEVES ANTITUMOR ACTIVITY IN BREAST CANCER BRAIN METASTASES IN VITRO AND IN VIVO
Breast cancer is the second most common primary tumor leading to brain metastases in adult cancer patients. Previous studies have shown that the PI3K/AKT/mTOR pathway in breast cancer brain metastasis is activated in up to 70% of analyzed tumors. However, there are no approved agents targeting this...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216688/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.195 |
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