CSIG-26. MOLECULAR DETERMINANTS OF SENSITIVITY TO PI3K/AKT/mTOR PATHWAY INHIBITION IN GLIOBLASTOMA

Molecular genetic aberrations in the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway are common in human cancers including glioblastoma, yet, novel therapeutic approaches targeting this pathway in glioblastoma have had limited success to date. Her...

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發表在:Neuro Oncol
Main Authors: von Achenbach, Caroline, Weller, Michael, Kaulich, Kerstin, Gramatzki, Dorothee, Zacher, Angela, Fabbro, Doriano, Reifenberger, Guido, Szabo, Emese
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216680/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.192
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