IMMU-58. REDUCED NEOANTIGEN EXPRESSION AS A POSSIBLE IMMUNE EVASION MECHANISM DURING GLIOMA PROGRESSION

Limited success of immune-based therapies in glioma might be in part due to the lack of enough neoantigens (neoAgs) that can be targeted by immune effector cells. In addition, gliomas also show dynamic clonal evolution over time, possibly leading to immunoediting during progression. In this study, w...

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Published in:Neuro Oncol
Main Authors: Nejo, Takahide, Matushita, Hirokazu, Karasaki, Takahiro, Nomura, Masashi, Nagae, Genta, Takayanagi, Shunsaku, Tanaka, Shota, Takahashi, Satoshi, Kitagawa, Yosuke, Hana, Taijun, Koike, Tsukasa, Narita, Yoshitaka, Nagane, Motoo, Nishikawa, Ryo, Ueki, Keisuke, Aburatani, Hiroyuki, Mukasa, Akitake, Kakimi, Kazuhiro, Saito, Nobuhito
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216610/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.561
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