EXTH-65. BET INHIBITION IN COMBINATION WITH TEMOZOLOMIDE TARGETS MYCN-POSITIVE GLIOBLASTOMA CELLS

Glioblastoma (GBM) is the most common malignant brain tumor in adults with a 15 month median survival after diagnosis. Patients receive surgical resection of the tumor, followed by aggressive radio- and chemotherapy with temozolomide (TMZ). Many human cancers including GBM demonstrate addiction to M...

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Published in:Neuro Oncol
Main Authors: Čančer, Matko, Drews, Lisa, Rosén, Gabriela, Westermark, Bengt, Nelander, Sven, Forsberg-Nilsson, Karin, Uhrbom, Lene, Weishaupt, Holger, Swartling, Fredrik
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216216/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.412
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