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MNGI-31. pFOXM1 PROTEIN EXPRESSION IN WHO GRADE III MENINGIOMAS CORRELATES WITH CDK4/6 GENOTYPE AND TRANSFORMATION HISTORY

BACKGROUND: World Health Organization (WHO) Grade III meningiomas are associated with poor clinical outcomes due to high rates of recurrence and limited adjuvant treatment options. The Forkhead Box M1 (FOXM1) transcription factor is a phosphorylation target of CDK4/6 that protects cancer cells from...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Mooney, Michael, So, Veronica, Tien, An-Chi, Derogatis, Alanna, Eschbacher, Jennifer, Stephenson, Christine, Mehta, Shwetal, Sanai, Nader
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216215/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.647
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