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OS8.1 A phase 0/2 clinical trial of a CDK4/6 inhibitor in aggressive meningioma patients

BACKGROUND: New approaches are urgently needed for aggressive meningiomas, which remain largely incurable. Forkhead Box M1 (FOXM1) has been identified as a master transcription factor in aggressive meningiomas and Cyclin D-dependent Kinases (CDK) are positive regulators of cell-cycle entry, promotin...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Tien, A, Li, J, Bao, X, DeRogatis, A, Fujita, Y, Pennington-Krygier, C, Kim, S, Mehta, S, Sanai, N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795112/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.051
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