ACTR-16. PERIPHERAL BLOOD CD4+ MONONUCLEAR CELL FRACTIONS ARE ASSOCIATED WITH OVERALL SURVIVAL AT FIRST RECURRENCE OF IDH-WILDTYPE GLIOBLASTOMA AFTER STANDARD CHEMORADIOTHERAPY: SECONDARY ANALYSES OF THE PHASE II DIRECTOR TRIAL

The alkylating agent temozolomide prolongs survival of glioblastoma patients through induction of futile DNA mismatch repair in cancer cells. Whether systemic temozolomide effects on the immune system affect outcome has not been studied in detail. To address this question, we analyzed peripheral blo...

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Publicado no:Neuro Oncol
Main Authors: Wirsching, Hans-Georg, Terksikh, Ekaterina, Silginer, Manuela, Krieg, Carsten, Tabatabai, Ghazaleh, Wick, Wolfgang, Reifenberger, Guido, Roth, Patrick, Becher, Burkhard, Weller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216167/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.050
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