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ACTR-16. PERIPHERAL BLOOD CD4+ MONONUCLEAR CELL FRACTIONS ARE ASSOCIATED WITH OVERALL SURVIVAL AT FIRST RECURRENCE OF IDH-WILDTYPE GLIOBLASTOMA AFTER STANDARD CHEMORADIOTHERAPY: SECONDARY ANALYSES OF THE PHASE II DIRECTOR TRIAL
The alkylating agent temozolomide prolongs survival of glioblastoma patients through induction of futile DNA mismatch repair in cancer cells. Whether systemic temozolomide effects on the immune system affect outcome has not been studied in detail. To address this question, we analyzed peripheral blo...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216167/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.050 |
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