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Diminished DEFA6 Expression in Paneth Cells Is Associated with Necrotizing Enterocolitis

BACKGROUND: Necrotizing enterocolitis (NEC) is the most common gastrointestinal disorder in premature infants with a high morbidity and mortality. Paneth cell dysfunction has been suggested to be involved in the pathogenesis of NEC. Defensin alpha-6 (DEFA6) is a specific marker for Paneth cells acti...

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Dettagli Bibliografici
Pubblicato in:Gastroenterol Res Pract
Autori principali: Markasz, Laszlo, Wanders, Alkwin, Szekely, Laszlo, Lilja, Helene Engstrand
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215571/
https://ncbi.nlm.nih.gov/pubmed/30420878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7345426
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