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Diminished DEFA6 Expression in Paneth Cells Is Associated with Necrotizing Enterocolitis

Background. Necrotizing enterocolitis (NEC) is the most common gastrointestinal disorder in premature infants with a high morbidity and mortality. Paneth cell dysfunction has been suggested to be involved in the pathogenesis of NEC. Defensin alpha-6 (DEFA6) is a specific marker for Paneth cells acti...

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Autores principales: Laszlo Markasz, Alkwin Wanders, Laszlo Szekely, Helene Engstrand Lilja
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2018-01-01
Colección:Gastroenterology Research and Practice
Acceso en línea:http://dx.doi.org/10.1155/2018/7345426
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