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Essential roles of mitochondrial and heme function in lung cancer bioenergetics and tumorigenesis

Contrary to Warburg’s hypothesis, mitochondrial oxidative phosphorylation (OXPHOS) contributes significantly to fueling cancer cells. Several recent studies have demonstrated that radiotherapy-resistant and chemotherapy-resistant cancer cells depend on OXPHOS for survival and progression. Several ca...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Kalainayakan, Sarada Preeta, FitzGerald, Keely E., Konduri, Purna Chaitanya, Vidal, Chantal, Zhang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215344/
https://ncbi.nlm.nih.gov/pubmed/30410721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0257-8
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