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Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression

Lung cancer remains the leading cause of cancer-related death, despite the advent of targeted therapies and immunotherapies. Therefore, it is crucial to identify novel molecular features unique to lung tumors. Here, we show that cyclopamine tartrate (CycT) strongly suppresses the growth of subcutane...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Kalainayakan, Sarada Preeta, Ghosh, Poorva, Dey, Sanchareeka, Fitzgerald, Keely E., Sohoni, Sagar, Konduri, Purna Chaitanya, Garrossian, Massoud, Liu, Li, Zhang, Li
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363760/
https://ncbi.nlm.nih.gov/pubmed/30723259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38345-1
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