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Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression

Lung cancer remains the leading cause of cancer-related death, despite the advent of targeted therapies and immunotherapies. Therefore, it is crucial to identify novel molecular features unique to lung tumors. Here, we show that cyclopamine tartrate (CycT) strongly suppresses the growth of subcutane...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Kalainayakan, Sarada Preeta, Ghosh, Poorva, Dey, Sanchareeka, Fitzgerald, Keely E., Sohoni, Sagar, Konduri, Purna Chaitanya, Garrossian, Massoud, Liu, Li, Zhang, Li
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363760/
https://ncbi.nlm.nih.gov/pubmed/30723259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38345-1
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