The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells

Vascular disrupting agents (VDAs) represent a promising class of anti-cancer drugs for solid tumor treatment. Here, we aim to better understand the mechanisms underlying tumor reccurrence and treatment resistance following the administration of a VDA, combretastatin A-4 phosphate (CA4P). Firstly, we...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Dey, Sanchareeka, Kumari, Sharda, Kalainayakan, Sarada Preeta, Campbell, James, Ghosh, Poorva, Zhou, Heling, FitzGerald, Keely E., Li, Maoping, Mason, Ralph P., Zhang, Li, Liu, Li
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790523/
https://ncbi.nlm.nih.gov/pubmed/29423106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23734
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