Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing

HIV-1 Tat protein is released from HIV-1-infected cells and can enter non-permissive cells including neurons. Tat disrupts neuronal homeostasis and may contribute to the neuropathogenesis in people living with HIV (PLWH). The use of cocaine by PLWH exacerbates neuronal dysfunction. Here, we examined...

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發表在:Sci Rep
Main Authors: Mohseni Ahooyi, Taha, Shekarabi, Masoud, Torkzaban, Bahareh, Langford, T. Dianne, Burdo, Tricia H., Gordon, Jennifer, Datta, Prasun K., Amini, Shohreh, Khalili, Kamel
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215004/
https://ncbi.nlm.nih.gov/pubmed/30390000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34539-9
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