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Perturbation of synapsins homeostasis through HIV-1 Tat-mediated suppression of BAG3 in primary neuronal cells

HIV-1 Tat is known to be released by HIV infected non-neuronal cells in the brain, and after entering neurons, compromises brain homeostasis by impairing pro-survival pathways, thus contributing to the development of HIV-associated CNS disorders commonly observed in individuals living with HIV. Here...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Mohseni Ahooyi, Taha, Torkzaban, Bahareh, Shekarabi, Masoud, Tahrir, Farzaneh G., Decoppet, Emilie A., Cotto, Bianca, Langford, Dianne, Amini, Shohreh, Khalili, Kamel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572798/
https://ncbi.nlm.nih.gov/pubmed/31209204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1702-2
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