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Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing

HIV-1 Tat protein is released from HIV-1-infected cells and can enter non-permissive cells including neurons. Tat disrupts neuronal homeostasis and may contribute to the neuropathogenesis in people living with HIV (PLWH). The use of cocaine by PLWH exacerbates neuronal dysfunction. Here, we examined...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Mohseni Ahooyi, Taha, Shekarabi, Masoud, Torkzaban, Bahareh, Langford, T. Dianne, Burdo, Tricia H., Gordon, Jennifer, Datta, Prasun K., Amini, Shohreh, Khalili, Kamel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215004/
https://ncbi.nlm.nih.gov/pubmed/30390000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34539-9
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