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Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing

HIV-1 Tat protein is released from HIV-1-infected cells and can enter non-permissive cells including neurons. Tat disrupts neuronal homeostasis and may contribute to the neuropathogenesis in people living with HIV (PLWH). The use of cocaine by PLWH exacerbates neuronal dysfunction. Here, we examined...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Mohseni Ahooyi, Taha, Shekarabi, Masoud, Torkzaban, Bahareh, Langford, T. Dianne, Burdo, Tricia H., Gordon, Jennifer, Datta, Prasun K., Amini, Shohreh, Khalili, Kamel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215004/
https://ncbi.nlm.nih.gov/pubmed/30390000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34539-9
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