Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer

Usnic acid (UA), a lichen secondary substance, has considerable anticancer activity in vitro, whereas its effect in vivo is limited. Here, potassium usnate (KU) was prepared by the salinization of UA to enhance its water solubility. KU showed increased bioavailability compared with UA in the tumor,...

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Publicado no:Sci Rep
Main Authors: Yang, Yi, Bae, Woo Kyun, Lee, Ji-Yoon, Choi, Yong Jae, Lee, Kyung Hwa, Park, Myong-Suk, Yu, Young Hyun, Park, So-Yeon, Zhou, Rui, Taş, İsa, Gamage, Chathurika, Paik, Man-Jeong, Lee, Jae Hyuk, Chung, Ik Joo, Kim, Kyung Keun, Hur, Jae-Seoun, Kim, Sang Kyum, Ha, Hyung-Ho, Kim, Hangun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214985/
https://ncbi.nlm.nih.gov/pubmed/30390003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34709-9
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