Deoxypodophyllotoxin Exerts Anti-Cancer Effects on Colorectal Cancer Cells Through Induction of Apoptosis and Suppression of Tumorigenesis

Deoxypodophyllotoxin (DPT) is a cyclolignan compound that exerts anti-cancer effects against various types of cancers. DPT induces apoptosis and inhibits the growth of breast, brain, prostate, gastric, lung, and cervical tumors. In this study, we sought to determine the effect of DPT on cell prolife...

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Detalhes bibliográficos
Main Authors: Chathurika D. B. Gamage, So-Yeon Park, Yi Yang, Rui Zhou, İsa Taş, Woo Kyun Bae, Kyung Keun Kim, Jung-Hyun Shim, Eunae Kim, Goo Yoon, Hangun Kim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-05-01
Colecção:International Journal of Molecular Sciences
Assuntos:
deoxypodophyllotoxin
tubulin polymerization
apoptosis
mitotic arrest
tumorigenic potentials
colorectal cancer
Acesso em linha:https://www.mdpi.com/1422-0067/20/11/2612
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