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Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine

Alcohol consumption has been shown to cause dysbiosis, but the mechanism involved in it is unknown. Recurrent colitis is known to induce expression of α-defensins in the colon, but the effect of alcohol consumption on it is not known. We investigated the effect of ethanol on α-defensin expression in...

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發表在:Sci Rep
Main Authors: Shukla, Pradeep K., Meena, Avtar S., Rao, Vaishnavi, Rao, Roshan G., Balazs, Louisa, Rao, RadhaKrishna
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214960/
https://ncbi.nlm.nih.gov/pubmed/30389960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34263-4
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