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Optogenetic dissection of mitotic spindle positioning in vivo
The position of the mitotic spindle determines the plane of cell cleavage, and thereby daughter cell location, size, and content. Spindle positioning is driven by dynein-mediated pulling forces exerted on astral microtubules, which requires an evolutionarily conserved complex of Gα∙GDP, GPR-1/2(Pins...
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| Gepubliceerd in: | eLife |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
eLife Sciences Publications, Ltd
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6214656/ https://ncbi.nlm.nih.gov/pubmed/30109984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38198 |
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