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Optogenetic dissection of mitotic spindle positioning in vivo

The position of the mitotic spindle determines the plane of cell cleavage, and thereby daughter cell location, size, and content. Spindle positioning is driven by dynein-mediated pulling forces exerted on astral microtubules, which requires an evolutionarily conserved complex of Gα∙GDP, GPR-1/2(Pins...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fielmich, Lars-Eric, Schmidt, Ruben, Dickinson, Daniel J, Goldstein, Bob, Akhmanova, Anna, van den Heuvel, Sander
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214656/
https://ncbi.nlm.nih.gov/pubmed/30109984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38198
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