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Two populations of cytoplasmic dynein contribute to spindle positioning in C. elegans embryos

The position of the mitotic spindle is tightly controlled in animal cells as it determines the plane and orientation of cell division. Contacts between cytoplasmic dynein and astral microtubules (MTs) at the cell cortex generate pulling forces that position the spindle. An evolutionarily conserved G...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Schmidt, Ruben, Fielmich, Lars-Eric, Grigoriev, Ilya, Katrukha, Eugene A., Akhmanova, Anna, van den Heuvel, Sander
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584144/
https://ncbi.nlm.nih.gov/pubmed/28739679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607038
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