LRP1 regulates smooth muscle contractility by modulating Ca(2+) signaling and expression of cytoskeletal related proteins.

OBJECTIVE: Mutations affecting contractile-related proteins in the extracellular matrix (ECM), microfibrils, or vascular smooth muscle cells (VSMCs) can predispose the aorta to aneurysms. We reported previously that the low-density lipoprotein receptor-related protein 1 (LRP1) maintains vessel wall...

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Dades bibliogràfiques
Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Au, Dianaly T., Ying, Zhekang, Hernández-Ochoa, Erick O., Fondrie, William E., Hampton, Brian, Migliorini, Mary, Galisteo, Rebeca, Schneider, Martin F., Daugherty, Alan, Rateri, Debra L., Strickland, Dudley K., Muratoglu, Selen C.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214382/
https://ncbi.nlm.nih.gov/pubmed/30354243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311197
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