Proprotein convertase inhibition promotes ciliated cell differentiation – a potential mechanism for the inhibition of Notch1 signalling by decanoyl‐RVKR‐chloromethylketone

Chronic repetitive rounds of injury and repair in the airway lead to airway remodelling, including ciliated cell loss and mucous cell hyperplasia. Airway remodelling is mediated by many growth and differentiation factors including Notch1, which are proteolytically processed by proprotein convertases...

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Guardat en:
Dades bibliogràfiques
Publicat a:J Tissue Eng Regen Med
Autors principals: Lee, Sang‐Nam, Choi, In‐Suk, Kim, Hyun Jun, Yang, Eun Jin, Min, Hyun Jin, Yoon, Joo‐Heon
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214225/
https://ncbi.nlm.nih.gov/pubmed/27878968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.2240
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