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Fibroblast-derived HGF drives acinar lung cancer cell polarization through integrin-dependent RhoA-ROCK1 inhibition

The formation of lumens in epithelial tissues requires apical-basal polarization of cells, and the co-ordination of this individual polarity collectively around a contiguous lumen. Signals from the Extracellular Matrix (ECM) instruct epithelia as to the orientation of where basal, and thus consequen...

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Bibliografiske detaljer
Udgivet i:Cell Signal
Main Authors: Datta, Anirban, Sandilands, Emma, Mostov, Keith E., Bryant, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214180/
https://ncbi.nlm.nih.gov/pubmed/28888686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.09.001
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