Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1

J-base binding protein 1 (JBP1) contributes to the biosynthesis and maintenance of base J (β-d-glucosylhydroxymethyluracil), a modification of thymidine confined to some protozoa. Camelid (llama) single-domain antibody fragments (nanobodies) targeting JBP1 were produced for use as crystallization ch...

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Bibliografiske detaljer
Udgivet i:Acta Crystallogr F Struct Biol Commun
Main Authors: van Beusekom, Bart, Heidebrecht, Tatjana, Adamopoulos, Athanassios, Fish, Alexander, Pardon, Els, Steyaert, Jan, Joosten, Robbie P., Perrakis, Anastassis
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2018
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213982/
https://ncbi.nlm.nih.gov/pubmed/30387773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18010282
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