The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1β by Human Cytomegalovirus through Inhibition of NF-kB Activity

Interleukin-1β (IL-1β) is a key effector of the inflammasome complex in response to pathogens and danger signals. Although it is well known that assembly of the inflammasome triggers proteolytic cleavage of the biologically inactive precursor pro-IL-1β into its mature secreted form, the mechanism by...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Biolatti, Matteo, Dell’Oste, Valentina, Scutera, Sara, Gugliesi, Francesca, Griffante, Gloria, De Andrea, Marco, Musso, Tiziana, Landolfo, Santo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213739/
https://ncbi.nlm.nih.gov/pubmed/30332797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10100567
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados