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ESCRT‐mediated lysosome repair precedes lysophagy and promotes cell survival

Although lysosomes perform a number of essential cellular functions, damaged lysosomes represent a potential hazard to the cell. Such lysosomes are therefore engulfed by autophagic membranes in the process known as lysophagy, which is initiated by recognition of luminal glycoprotein domains by cytos...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Radulovic, Maja, Schink, Kay O, Wenzel, Eva M, Nähse, Viola, Bongiovanni, Antonino, Lafont, Frank, Stenmark, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213280/
https://ncbi.nlm.nih.gov/pubmed/30314966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899753
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