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Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation

The endosomal sorting complex required for transport (ESCRT) machinery mediates cargo sorting, membrane deformation and membrane scission on the surface of endosomes, generating intraluminal vesicles (ILVs) to degrade signaling receptors. By live-cell imaging of individual endosomes in human cells,...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wenzel, Eva Maria, Schultz, Sebastian Wolfgang, Schink, Kay Oliver, Pedersen, Nina Marie, Nähse, Viola, Carlson, Andreas, Brech, Andreas, Stenmark, Harald, Raiborg, Camilla
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062606/
https://ncbi.nlm.nih.gov/pubmed/30050131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05345-8
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