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Attempt to Untangle the Prion-Like Misfolding Mechanism for Neurodegenerative Diseases

The misfolding and aggregation of proteins is the neuropathological hallmark for numerous diseases including Alzheimer’s disease, Parkinson’s disease, and prion diseases. It is believed that misfolded and abnormal β-sheets forms of wild-type proteins are the vectors of these diseases by acting as se...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Autor principal: Sarnataro, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213118/
https://ncbi.nlm.nih.gov/pubmed/30304819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103081
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