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Attempt to Untangle the Prion-Like Misfolding Mechanism for Neurodegenerative Diseases

The misfolding and aggregation of proteins is the neuropathological hallmark for numerous diseases including Alzheimer’s disease, Parkinson’s disease, and prion diseases. It is believed that misfolded and abnormal β-sheets forms of wild-type proteins are the vectors of these diseases by acting as se...

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Vydáno v:Int J Mol Sci
Hlavní autor: Sarnataro, Daniela
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213118/
https://ncbi.nlm.nih.gov/pubmed/30304819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103081
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